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The primary goal of alveolar ridge preservation procedures is volume preservation, the volume preserved by encouraging new bone formation in healing sockets. About 90% of patients referred for implant therapy must perform these procedures after extraction that employs the placement of grafting materials. Objective: Evaluate and characterize the healing responses of Growth hormone, and bicalcium phosphate mixture in tooth extraction sockets of a canine model. Materials and Methods: Six mongrel dogs were included in this study; they were divided into 2 groups according to the time of sacrifice (4 and 8 weeks). Each of these groups includes three animals. Animals were subjected to extraction of the third premolar bilaterally, The right side was treated with a mixture of 4 IU (1.6mg) Growth hormone and easy-graft TM (a composite of hydroxyapatite and bèta-tricalcium phosphate – crystal ) 1 x 0.15 ml (450-650 μm) in a granular form before wound closure while the left side was left as a control. The healing extraction sockets were evaluated by Fourier Transform Infrared spectroscopic analysis. Results: All sockets healed without complications. Growth hormone and biphasic calcium phosphate groups showed new bone formation comparable to that of native bone. Conclusion: The grafted sockets demonstrated acceptable biodegradability at 4 and 8 weeks postoperatively. The new bone formation was not delayed because of the graft.

egyptian dental journal /egyptian dental journal

FOURIER TRANSFORM INFRARED SPECTROSCOPIC ANALYSIS FOR HEALING SOCKETS TREATED WITH A MIXTURE OF GROWTH HORMONE AND BIPHASIC CALCIUM PHOSPHATE: EXPERIMENTAL STUDY ON DOGS