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Periodontal disease involves complex interactions between bacterial products; host cells and locally produced biologically active factors. The role of cytokines, IL-1 beta and IL-6, in periodontal disease pathogenesis has been widely reported. In this study, we studied the role of periodontal treatment with and without oral hygiene measures through measuring the level of these cytokines in cervical gingival fluid and in gingival tissues. The study results demonstrated that the level of cytokines decreased after dental treatment without application of oral hygiene measures, but their levels decreased significantly if the dental treatment was associated with oral hygiene measures. This indicated that oral hygiene measures are important for better chronic periodontitis treatment.

egyptian dental journal /egyptian dental journal

EFFECTS OF SCALING AND ROOT PLANING WITH OR WITHOUT ORAL HYGIENE MEASURES ON THE TREATMENT OF CHRONIC PERIODONTITIS: AN IMMUNOHISTOCHEMICAL AND CLINICO-BIOCHEMICAL STUDY