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Our study established the histopathlogical effect of different dosages malathion on the third larval instar of Chrysomya megacephala. The concentration of malathion increased gradually during the larval stages reaching the maximum concentration in the third instar larvae.The midgut of third larval instar was studied using transmission electron microscope. The most significant alterations were increasing damage to the larvae midgut including columnar prominent ,fat vacuoles, atrophied microvilli. These results indicate that malathion retard larval development.

Ultrastructure of the Midgut of theThird Larval Instar of Chrysomya megacephala (Diptera:Calliphoridae) fed on malathion treated diet