English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

There are no uses for the strychnine tree (Strychnos nux-vomica L.) in modern medicine although it was widely used in medicine before World War II. The properties of Nux Vomica are those of the alkaloid strychnine. Herein we investigated phytochemically the aqueous methanolic extract of the S. Nux vomica and isolated five phenolic compounds; Kaempferol-7 Glucoside 1, 7 hydroxy Coumarin 2, Quercetin-3-Rhamnoside 3, Kaempferol 3-rutinoside 4, and Rutin 5. At the same time, the cytotoxic activity of the extract was evaluated against different cancer cell lines. The extract showed potential cytotoxic activity against human epidermoid larynx carcinoma cells, with IC50 value 17.8 μg/mL. It also exhibited promising cytotoxic activity against breast carcinoma cell line (MCF-7) with IC50 36.3 μg/mL. Colon carcinoma cells were the least one affected by the extract as its IC50 was 41.2 μg/mL.

PHYTOCHEMICL AND ANTIPROLIFERATIVE INVESTIGATIONS OF STRYCHNOS NUX-VOMICA LEAVES