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A new [1,5]-benzodiazepines (VI) were synthesized by the reaction of ophenylenediamine with 2-chloro-3-acetylquinoline in the presence of tetrabutyl ammonium bromide (TBAB) in short reaction time with excellent yield.

ONE-POT SYNTHESIS AND ANTIMICROBIAL SCREENING OF NEW [1,5] –BENZODIAZEPINE DERIVATIVES CATALYZED BY TBAB