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Background: Postmenopausal bleeding (PMB), defined as blood loss occurring at least 12 months after menopause, is a common complaint in general gynecological practice. The prevalence of PMB is approximately 10% immediately after menopause. Aim of work: This study aims to compare between two diagnostic methods Flush and Brush cytology. Patients and Methods: The study population comprises eighty (80) women with postmenopausal bleeding, was conducted over 12 months from April 2018, to April 2019 on postmenopausal women who were approached, managed and followed up in the Gynecology Clinic of Minia General Hospital to compare between two diagnostic methods Flush and Brush cytology. Results: The statistical results showed that the subjective pain varied significantly between the three methods. However, that difference was too little to be of clinical value. On the other hand, the objective pain showed no statistically significant difference between the three methods. Regarding tissue yield, the D&C method provided significantly more adequate samples (88.8%) compared with both the flush (30%) and brush (53.8%) methods (p-values, <0.05). Also, the difference between the brush and flush methods was also statistically significant (p-value <0.05). Conclusion: Flush and brush are simple methods, associated with comparable pain scores. However, they have modest tissue yield which limits their clinical applicability in the screening of endometrial abnormalities in patients with postmenopausal bleeding.

Endometrial Flushing Versus Endometrial Brush Cytology in High Risk Women for endometrial carcinoma