English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Key word: Resistin; Visfatin; inflammatory bowel disease Background and study aim: Ulcerative colitis (UC) and Crohn's disease (CD) are the common forms of inflammatory bowel disease (IBD). The etiology and pathogenesis are not fully understood yet. Many studies have been focused on adipokines in the pathogenesis of IBD. IBD is associated with alteration in fat distribution and development of white adipose tissue (WAT) hypertrophy in the mesentery. Most of adepokines are formed in WAT or in immune cells and play an important role in IBD manifestations. The aim of this study was to evaluate the levels of resistin and visfatin in IBD patients before and after treatment. Patients and Methods: 40 patients with IBD who(15 patients with CD and 25 patients with UC) attended to Tropical Medicine and Internal Medicine Departments; Zagazig University Hospitals from March 2012 till December 2013 were included in this study. Serum levels of resistin and visfatin were measured before treatment and 3 months after the treatment. Results: The mean serum levels of resistin in Crohn's disease ranged from 12.2+2 ng/ml to 9.0 + 4.0 (P= 0.1) and the mean serum levels of visfatin in Crohn's disease ranged from 5.6+4.6 ng/ml to 3.4+4.1 ng/ml (P= 0.04) before and after treatment respectively, and the mean serum levels of resistin in ulcerative colitis ranged from 11.2+2 ng/ml to 7.5+ 3.1 ng/ml (P= 0.039) and the mean serum levels of visfatin in ulcerative colitis ranged from 3.7+1.2 to 2.5+1.1 ng/ml (P= 0.004) before and after treatment respectively. Conclusion: The serum levels of resistin and visfatin decreased significantly after treatment induction for IBD , so can be used as a marker for treatment success.

Circulating Resistin and Visfatin Levels in Patients with Inflammatory Bowel Disease as Predictors of Treatment Response