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Background and Study aim: Diuretic resistance in patients with cirrhosis is clinically manifested by the failure to lose weight or ascetic volume despite high dosages of loop diuretics and sodium restriction. Natriuretic peptides(NP) promote natriuresis and diuresis. Atrial natriuretic peptide (ANP) is known to act as a rapid response hormone and Brain natriuretic peptide( BNP) more as a “back up hormone” activated only after prolonged ventricular overload .Pro BNP are more stable and have been suggested to have a longer biological half life than other natriuretic peptides .

Serum Level of pro Brain Type Natriuretic Peptide in Diuretic Resistance and Diuretic Respondent Ascites in Cirrhotic Patients