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Pathological syndromes caused by avian hepatitis E virus (aHEV) have been described under different names, depending on the country in which they were observed. The most commonly used terms are big liver and spleen disease (BLS), hepatitis-splenomegaly syndrome (HSS) (1), necrotic, haemorrhagic, hepatomegalic hepatitis, or hepatitis-liver haemorrhage syndrome (1, 6, 8, 11, 22). In Poland, the first description of a clinical case of BLS was presented in 2011 at the 1st Veterinary Practice Congress in Łódź (31), although field practitioners had already been observing this syndrome for a few years, at least from 2007 (33).

Classification, structure and molecular diagnostics of avian hepatitis E virus