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An ultrastructural study of African endemic Kaposi's sarcoma (KS) of the skin and lymph nodes revealed an irregularity of blood vascular tissues and prominent diapiresis of erythrocytes in the early stage of the disease. In the advanced stage, incomplete blood capillary structures covered with primitive mesenchymal cells were observed. Erythrophagia was frequently seen. These results suggest that KS cells are derived from primitive mesenchymal cells which may differentiate to immature endothelial cells.

An Ultrastructural Study of African Endemic Kaposi's Sarcoma.