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This study evaluates the nutritional, Haematinic and biosafety of Ipomoea batatas (L.) Lam. (Solanales: Convolvulaceae) aqueous leaf extract on albino rats. Proximate and mineral compositions were determined using standard methods. Haematinic activity of the plant was done using graded doses; 125, 250, and 500 mg/kg and 40 mg/kg phenyl hydrazine hydrochloride to induce anaemia. A modified method was used for acute and sub-acute toxicological evaluations. Results from the study showed that aqueous extracts of I. batatas had significant increase in RBC, HCT, Hgb, MCV, MCH and MCHC at 7.19±0.45, 46.13±0.08, 13.43±0.27, 82.40±0.92, 24.15±1.24 and 37.78±0.20, respectively, when compared with the control group. Acute study showed no pathological behaviour with absent mortality. Sub-acute study of the spleen, heart, liver and kidney showed a mild activation of local immune system. The extracts recorded 89.14% scavenging property compared with 94.3% ascobate in antioxidant study. Proximate analysis had 31.56% of moisture content, 16.25% of protein, 7.64% of ash, 0.37% of crude fibre, 0.19% of fat and 43.99% of carbohydrate. Investigation of calcium, magnesium, Iron, potassium, phosphorus, sodium and zinc were 28.03, 339.61, 15.87, 4.61, 35.90, 4.21 and 0.08 mg/kg others were not detected. This may be due to stimulating mechanism of Myelo-Erythroid cell ratio in bone marrow or antioxidant effect. Result thus validates ethnobotanical uses of I. batatas for the treatment of anaemia.

Nutritional, haematinic and biosafety evaluation of Ipomoea batatas (L.) Lam. (Solanales: Convolvulaceae) leaf extract on albino rats