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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute life-threatening adverse drug reactions (ADRs) that are commonly caused by medications. Apart from their contribution to morbidity and mortality, these diseases may also present substantial consequences on health care resources. In this study, we aimed to identify the incidence, causative drugs, and economic consequences of these serious ADRs and potential drug-drug interactions (DDIs) during treatment.

therapeutics and clinical risk management

Incidence, causative drugs, and economic consequences of drug-induced SJS, TEN, and SJS&amp;ndash;TEN overlap and potential drug&amp;ndash;drug interactions during treatment: a retrospective analysis at an Indonesian referral hospital