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The therapeutic effect of a once-daily oral drug will be maintained if there are no occurrences of consecutively missed doses that exceed the duration of the drug's effect. The durations of effect of antiretroviral drugs are typically in the range of 1-4 days. Here, we report the observed frequencies of ≥2, ≥3, and ≥4 consecutively missed doses for patients taking a once-daily oral antiretroviral drug for HIV infection.

<p>Patterns of non-adherence to oral antiretroviral medication: frequencies of consecutively missed doses</p>