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The aim of this study was to propose an alternative approach to item response theory (IRT) in the development of computerized adaptive testing (CAT) in quality of life (QoL) for patients with multiple sclerosis (MS). This approach relied on decision regression trees (DRTs). A comparison with IRT was undertaken based on precision and validity properties.

patient preference and adherence

Computerized adaptive testing with decision regression trees: an alternative to item response theory for quality of life measurement in multiple sclerosis