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This study aims to evaluate the influence of genetic polymorphisms of CYP2D6, CYP3A5, ABCB1 , and APOE genes and nongenetic factors on steady-state plasma concentrations (Cpss) of donepezil and therapeutic outcomes in Thai patients with Alzheimer's disease (AD) and vascular dementia (VAD).

pharmacogenomics and personalized medicine

&lt;p&gt;Influence of &lt;em&gt;CYP2D6, CYP3A5, ABCB1, APOE&lt;/em&gt; polymorphisms and nongenetic factors on donepezil treatment in patients with Alzheimer’s disease and vascular dementia&lt;/p&gt;