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The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate the influence of the PPP3CA c.249G&gt;A variant on the clinical outcomes of kidney transplant recipients.

pharmacogenomics and personalized medicine

Association of the &lt;em&gt;PPP3CA&lt;/em&gt; c.249G&amp;gt;A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients