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Poly (ADP-ribose) polymerase 1 (PARP1) has an important role in homologous recombination repair. The purpose of this study was to investigate the effect of PARP1 inhibitor on oxaliplatin treatment for colorectal cancer (CRC).

Combined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and &gamma;-H2AX foci formation in colorectal cancer

Combined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and γ-H2AX foci formation in colorectal cancer