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Restoring lost function to suppressor gene products has captured the interest of the research community in the field of gene therapy. AKAP12 , also known as Gravin/AKAP250 , is a tumor suppressor gene, and its deregulation may be responsible for cancer progression. The aim of this study was to investigate whether AKAP12 mRNA has an anti-cancer function by regulating onco-miRNA expression in colorectal cancer (CRC) cells.

oncotargets and therapy

&lt;p&gt;&lt;em&gt;AKAP12&lt;/em&gt; Endogenous Transcripts Suppress The Proliferation, Migration And Invasion Of Colorectal Cancer Cells By Directly Targeting oncomiR-183-5p&lt;/p&gt;