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Tongue squamous cell carcinoma (TSCC) is the second most common malignancy in oral carcinoma. lncRNA metastasis-associated lung adenocarcinoma transcript 1 ( MALAT1 ) was regarded as an oncogenic factor in various carcinomas. However, its underlying molecular mechanisms in the development and progression of TSCC have not been well featured till now.

oncotargets and therapy

&lt;p&gt;lncRNA &lt;em&gt;MALAT1&lt;/em&gt; potentiates the progression of tongue squamous cell carcinoma through regulating &lt;em&gt;miR-140-5p&lt;/em&gt;-PAK1 pathway&lt;/p&gt;