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Breast cancer (BC) is a highly heterogeneous disease presenting a broad range of clinical and molecular characteristics. In the past years, a growing body of evidence demonstrated that immune response plays a significant role in cancer outcome. However, immune prognostic markers are not completely validated in clinical practice in BC patients.

oncotargets and therapy

High neutrophil to lymphocyte ratio and decreased CD69&lt;sup&gt;+&lt;/sup&gt;NK cells represent a phenotype of high risk in early-stage breast cancer patients