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Obesity is a complex and multifactorial disease identified as a global epidemic. Convergent evidence indicates that obesity differentially influences patients with neuropsychiatric disorders providing a basis for hypothesizing that obesity alters brain structure and function associated with the brain's propensity toward disturbances in mood and cognition. Herein, we characterize alterations in brain structures and networks among obese subjects (ie, body mass index [BMI] ≥30 kg/m 2 ) when compared with non-obese controls.

Brain structural networks and connectomes: the brain&ndash;obesity interface and its impact on mental health

Brain structural networks and connectomes: the brain–obesity interface and its impact on mental health