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Early-onset Alzheimer's disease (AD) accounts for than less 1% of all AD cases, with large variation in the reported genetic contributions of known dementia genes. Mutations in the amyloid precursor protein ( APP ) gene were the first to be recognized as the cause of AD.

Identification of a novel mutation in <em>APP</em> gene in a Thai subject with early-onset Alzheimer&#39;s disease

Identification of a novel mutation in <em>APP</em> gene in a Thai subject with early-onset Alzheimer's disease