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Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder causing intrusive thoughts or repetitive behaviors. Serotonin reuptake inhibitors are used for OCD treatment, but 40%-60% of patients do not respond to them adequately. In this study, the associations of serotonin receptor 2a polymorphisms rs6311 and rs6313 with OCD, its familial form and fluvoxamine treatment response in Iranian population were investigated.

neuropsychiatric disease and treatment

Association of serotonin receptor 2a haplotypes with obsessive&amp;ndash;compulsive disorder and its treatment response in Iranian patients: a genetic and pharmacogenetic study