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Tumor necrosis factor-α (TNF-α) and IL-1β are 2 pro-inflammatory cytokines known to be involved in rheumatic diseases. The therapeutic strategy used in micro-immunotherapy (MI) to reduce chronic inflammation and attenuate pain consists in mainly targeting these 2 cytokines. 2LARTH ® is a sublingually administered medicine consisting of lactose-saccharose globules impregnated with ethanolic preparations of immune mediators and nucleic acids at ultra-low doses.

journal of inflammation research

2LARTH&lt;sup&gt;&amp;reg;&lt;/sup&gt;, a micro-immunotherapy medicine, exerts anti-inflammatory effects in vitro and reduces TNF-&amp;alpha; and IL-1&amp;beta; secretion