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There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. In this study, AR symptoms were evaluated before and after daily 1 mg/mL rupatadine oral solution administration in 2-5-year-old children.

Rupatadine oral solution for 2&ndash;5-year-old children with allergic rhinitis: a safety, open-label, prospective study

Rupatadine oral solution for 2–5-year-old children with allergic rhinitis: a safety, open-label, prospective study