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Circinal-icaritin (CIT), one new active aglycone of Epimedium, can exert a beneficial effect on osteoporotic bone. However, its low bioavailability limits its clinical efficacy for the treatment of osteoporosis.

international journal of nanomedicine

Mechanism of enhanced antiosteoporosis effect of&amp;nbsp;circinal&amp;ndash;icaritin by self-assembled nanomicelles&amp;nbsp;in vivo with suet oil and sodium deoxycholate