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Reactive oxygen species (ROS)-induced oxidative stress plays a key role in the pathogenesis and progression of psoriasis by causing inflammation. Antioxidative strategies eradicating ROS may serve as effective and easy treatment options for psoriasis, while nanozymes with intrinsic antioxidant enzyme-like activity have not been explored for psoriasis treatment. The aim of this study is to fabricate β-cyclodextrins (β-CDs)-modified ceria nanoparticles (β-CDs/CeO 2 NPs) with drug-loaded and multimimic-enzyme activities for combinational psoriasis therapy.

international journal of nanomedicine

&lt;p&gt;Cyclodextrin-Modified CeO&lt;sub&gt;2&lt;/sub&gt; Nanoparticles as a Multifunctional Nanozyme for Combinational Therapy of Psoriasis&lt;/p&gt;