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Rehmannia glutinosa polysaccharide is the main reason that contributes to the immunological function of R. glutinosa . Due to its disadvantages in clinical use, here we designed the PEGylation nano-RGP (pRL) to improve the drug-targeting effect and the immunological function. Our present work aims to establish the optimum condition of preparing the pRL and to investigate its immunological function on macrophages.

international journal of nanomedicine

&lt;p&gt;Optimum Preparation Method for Self-Assembled PEGylation Nano-Adjuvant Based on &lt;em&gt;Rehmannia glutinosa Polysaccharide&lt;/em&gt; and Its Immunological Effect on Macrophages&lt;/p&gt;