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Fungal keratitis (FK) is a serious pathogenic condition usually associated with significant ocular morbidity. Natamycin (NAT) is the first-line and only medication approved by the Food and Drug Administration for the treatment of FK. However, NAT suffers from poor corneal penetration, which limits its efficacy for treating deep keratitis.

international journal of nanomedicine

&lt;p&gt;Natamycin solid lipid nanoparticles &amp;ndash; sustained ocular delivery system of higher corneal penetration against deep fungal keratitis: preparation and optimization&lt;/p&gt;