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To evaluate the adverse vascular effects of nanoparticles (NPs) in vitro, extensive studies have investigated the toxicity of NPs on endothelial cells, but the knowledge of potential toxicity on human smooth-muscle cells (SMCs) is currently limited.

A comparative study of toxicity of TiO<sub>2</sub>, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells