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Titanium dioxide nanoparticles (TiO 2 NPs) represent a scientific breakthrough in the areas of biological and medicinal applications. Interaction of TiO 2 NPs with components of innate immune system remains elusive.

international journal of nanomedicine

Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation