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Core-shell-structured nanoparticles (NPs) have attracted much scientific attention due to their promising potential in biomedical fields in recent years. However, their underlying mechanisms of action and potential adverse effects following administration remain unknown.

international journal of nanomedicine

Biological responses to core&amp;ndash;shell-structured Fe&lt;sub&gt;3&lt;/sub&gt;O&lt;sub&gt;4&lt;/sub&gt;@SiO&lt;sub&gt;2&lt;/sub&gt;-NH&lt;sub&gt;2&lt;/sub&gt; nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy