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Erythrocyte aggregation, a cardiovascular risk factor, is increased by high plasma fibrinogen levels. Here, the effect of different fibrinogen mutations on binding to its human erythrocyte receptor was assessed in order to identify the interaction sites.

international journal of nanomedicine

The &lt;sub&gt;95&lt;/sub&gt;RGD&lt;sub&gt;97&lt;/sub&gt; sequence on the A&amp;alpha; chain of fibrinogen is essential for binding to its erythrocyte receptor