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Parkinson's disease (PD) is a chronic neurodegenerative disorder. There is limited knowledge about the function of the hypothalamic-pituitary-adrenal axis in PD. The primary aim of this prospective study was to analyze diurnal salivary cortisol concentrations in patients with PD and correlate these with age, gender, body mass index (BMI), duration of PD, and pain. The secondary aim was to compare the results with a healthy reference group.

Diurnal salivary cortisol concentrations in Parkinson&rsquo;s disease: increased total secretion and morning cortisol concentrations

Diurnal salivary cortisol concentrations in Parkinson’s disease: increased total secretion and morning cortisol concentrations