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The occurrence and development of antibiotic resistance are mainly caused by the spread of large plasmids carrying multiple antibiotic resistance genes. Recently, the association between 16S rRNA methyltransferase genes and β-lactamase genes carried by the same plasmid is of concern.

infection and drug resistance

&lt;p&gt;Coexistence of &lt;em&gt;bla&lt;/em&gt;&lt;sub&gt;NDM-1&lt;/sub&gt; and &lt;em&gt;rmtC&lt;/em&gt; on a Transferrable Plasmid of a Novel ST192 &lt;em&gt;Klebsiella aerogenes&lt;/em&gt; Clinical Isolate&lt;/p&gt;