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Drug resistance to nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), and protease inhibitors (PIs) has been associated with loss of viral suppression measured by a rise in HIV-1 RNA levels, a decline in CD4 cell counts, persistence on a failing treatment regimen, and lack of adherence to combination antiretroviral therapy.

High rate of HIV-1 drug resistance in treatment failure patients in Taiwan, 2009&ndash;2014

High rate of HIV-1 drug resistance in treatment failure patients in Taiwan, 2009–2014