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Artemisinin resistance in Plasmodium falciparum is suspected when the day 3 parasitemia is &gt;10% when treated with artemisinin-based combination therapy or if &gt;10% of patients treated with artemisinin-based combination therapy or artesunate monotherapy harbored parasites with half-lives ≥5 hours. Hence, a single-arm prospective efficacy trial was conducted in Suriname for uncomplicated P. falciparum infection treated with artesunate-based monotherapy for 3 days assessing day 3 parasitemia, treatment outcome after 28 days, and parasite half-life.

Assessing parasite clearance during uncomplicated <em>Plasmodium falciparum </em>infection treated with artesunate monotherapy in Suriname