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MetaGeM is a wide gender-medicine project comprising post hoc and meta-analyses by gender of clinical outcomes, therapeutic approaches, and safety data from previously conducted observational studies to explore possible gender differences in real-life clinical settings. We report the results of the safety meta-analysis of seven MetaGeM studies, evaluating gender differences in adverse event (AE) incidence and severity.

drug design, development and therapy

Gender differences in the adverse events&rsquo; profile registered in seven observational studies of a wide gender-medicine (MetaGeM) project: the MetaGeM safety analysis