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β-asarone, an active component of Acori graminei rhizome, has been reported to have neuroprotective effects in Alzheimer's disease. As the underlying mechanism is not known, we investigated the neuroprotective effects of β-asarone in an APP/PS1 double transgenic mouse model and in NG108 cells.

drug design, development and therapy

Neuroprotective effect of &amp;beta;-asarone against Alzheimer&amp;rsquo;s disease: regulation of synaptic plasticity by increased expression of SYP and GluR1