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Carvedilol is a third-generation β-blocker indicated for congestive heart failure and high blood pressure. The aim of this study was to investigate the dose proportionality of the carvedilol sustained-release (SR) formulation in healthy male subjects.

drug design, development and therapy

Dose proportionality and pharmacokinetics of&amp;nbsp;carvedilol sustained-release formulation: a&amp;nbsp;single dose-ascending 10-sequence incomplete block study