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There is no effective treatment for liver fibrosis, which is a common phase during the progression of many chronic liver diseases to cirrhosis. Previous studies found that Semen Brassicae therapy can effectively improve the clinical symptoms of patients with asthma, allergic rhinitis, and chronic lung diseases; however, its effects on liver fibrosis in rats and its possible mechanisms of action remain unclear.

drug design, development and therapy

Semen Brassicae ameliorates hepatic fibrosis by regulating transforming growth factor-&amp;beta;1/Smad, nuclear factor-&amp;kappa;B, and AKT signaling pathways in rats