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Ocular hypertension is an important risk factor for glaucoma. The purpose of this study was to investigate the gliotoxic effects of α-aminoadipic acid (AAA) in a rat model of AOH and its underlying mechanisms.

drug design, development and therapy

&amp;alpha;-Aminoadipic acid protects against retinal disruption through attenuating M&amp;uuml;ller cell gliosis in a rat model of acute ocular hypertension