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Aprepitant (Emend ® ) is a novel antiemetic agent that works through antagonism of neurokinin-1 (NK-1) receptors. To date, there are limited data regarding its use to prevent postoperative nausea and vomiting (PONV) in children. We retrospectively reviewed our initial 12-months experience with aprepitant after it was made available for perioperative use.

clinical pharmacology

&lt;p&gt;Perioperative Administration of Emend&lt;sup&gt;®&lt;/sup&gt; (Aprepitant) at a Tertiary Care Children’s Hospital: A 12-Month Survey&lt;/p&gt;