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The objective of the present study was to explore the molecular mechanism by which a single nucleotide polymorphism (rs712) interferes with interaction between 3'-untranslated region (3'-UTR) of KRAS and let-7g, and its association with development of lung cancer in the patients with COPD.

international journal of chronic obstructive pulmonary disease/international journal of copd

A variant in 3&amp;#39;-untranslated region of KRAS compromises its interaction with hsa-let-7g and&amp;nbsp;contributes to the development of lung cancer in&amp;nbsp;patients with COPD