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O associated with a high backup ventilator rate) may improve adherence, physiological, and subjective outcomes when compared with delivery of high pressure noninvasive mechanical ventilation (without elevated backup respiratory rate). The authors concluded that both strategies are equivalent in all the recorded outcomes, showing thus that driving pressure, but not backup respiratory rate, is essential to gain physiological and clinical benefits in this population when in a chronic stable condition.Despite previous randomized studies showing the potential benefits of long-term noninvasive mechanical ventilation in hypercapnic patients with chronic obstructive pulmonary disease, current research has still not clearly indicated the best strategy to improve the patient’s adherence with treatment.

Noninvasive mechanical ventilation with high pressure strategy remains a &ldquo;double edged sword&rdquo;?

Noninvasive mechanical ventilation with high pressure strategy remains a “double edged sword”?