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Correspondence: Filip Geurs regional Hospital sint Maria, Ziekenhuislaan 100, B1500 Halle, Belgium Tel +32 2 363 66 10 Fax +32 2 363 6264 email g@regzhsintmaria.be Abstract: After failure of cisplatin-based chemotherapy for metastatic urachal carcinoma, a 16-year-old patient presents with diffuse liver-, lung-, and brain metastases. The K-ras mutation is present in the liver as well as in the primary resected specimen. The regimen was therefore changed to bevacizumab, 5-fluorouracil, and irinotecan. This led to a partial response which lasted 7 months.

clinical oncology in adolescents and young adults

Urachal carcinoma with liver, lung, and brain metastases: benefit of a new combination chemotherapy (bevacizumab, 5-fluorouracil, irinotecan) &amp;ndash; case report