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To compare the efficacy of rituximab, dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (R-DA-EPOCH) with traditional rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) regimens in double-hit lymphoma (DHL) and gene copy number gain (CNG) lymphoma and to contrast the prognosis of these two disease types.

cancer management and research

&lt;p&gt;Efficacy of dose-adjusted EPOCH plus rituximab/R-CHOP regimens and the prognosis analysis in patients with &lt;em&gt;MYC&lt;/em&gt;, &lt;em&gt;BCL2/BCL6&lt;/em&gt; gene copy number gain lymphoma and double-hit lymphoma: results from a single institution retrospective clinical study&lt;/p&gt;