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To study the prognostic value of klotho ( KL) and its promoter DNA methylation in head and neck squamous cell carcinoma (HNSCC) and to assess their associations with the autophagy gene LC3 and the RNA transferase gene NSUN2.

<p>DNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma</p>