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The spectrum of BRCA mutations that predispose to development of breast/ovarian cancer in Indian population remains unexplored. We report incidence and various types of pathogenic, likely pathogenic and variants of unknown significance (VUS) mutations in BRCA1 and BRCA2 genes observed at a tertiary cancer center in North India.

cancer management and research

Germline &lt;em&gt;BRCA1&lt;/em&gt; and &lt;em&gt;BRCA2&lt;/em&gt; deleterious mutations and variants of unknown clinical significance associated with breast/ovarian cancer: a report from North India