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Human melanoma is a malignant tumor originated from melanocytes with high invasion, metastasis, and poor prognosis. In this study, the effects of naphthalimides UNBS5162 and amonafide on the properties of proliferation and apoptosis in human melanoma cells were confirmed.

<p>UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway</p>